Poster 449 Ketotic Hypoglycemia in RYR‐1 Central Core Myopathy: A Case Report

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147182/1/pmr2s344a.pd

The Crystal Structures of Some Organic Molecules

This thesis deals with the elucidation of the crystal and molecular structures of some organic molecules using X-ray diffraction methods. The thesis is divided into four parts. In Part I the process of X-ray crystal analysis is described briefly, and some methods of overcoming the fundamental difficulty in crystal analysis - the phase problem - and obtaining an approximate structure are outlined. Many investigations however are undertaken with the object of obtaining accurate molecular dimensions, and methods of refining a structure are described in Part II. The use of (Fo - Fc ) syntheses is illustrated by the refinements of the crystal structures of p-benzoquinone and coronene. More accurate values of the bond lengths and valency angles in benzoquinone have been obtained, and these agree reasonably well with those obtained in an electron-diffraction Investigation of the vapour, and with those in related molecules. In the coronene refinement, the discrepancies between measured and calculated bond lengths have been reduced, and the hydrogen atoms have been resolved. Part III describes the analysis of the structure of dinaphthoperopyrene, an "overcrowded" polynuclear aromatic hydrocarbon. An interesting series of regions of diffuse scattering indicates the presence of a stacking disorder, but in spite of this the molecular dimensions have been determined with considerable precision. The molecule is distorted so that the distance between the overcrowded carbon atoms is 2.95 A, but this separation is achieved with little variation of the valency angles from 120, and this probably explains the retention of aromatic character in spite of the severe distortion. Part IV is an account of the determination of the structures of diindenyl iron and diindenyl cobalt. The "sandwich" nature of these molecules is well illustrated in the projections along two crystal axes. The aromatic rings in these molecules are probably rotating freely in solution and in the vapour state, but fixed in the crystal, and it has been postulated that the configuration is probably trans. While the present analysis has not yielded accurate molecular dimensions (a three-dimensional analysis will be required), It does show definitely that the molecular configuration in the crystal is not trans, but gauche

A Survey of the Present Status of Classroom Music in the Tacoma Public Schools

The purpose of this study was (1) to survey teachers of grades four, five and six in the Tacoma School System to determine how many believe music should be taught by a special music teacher, the classroom teacher, or both; (2) to determine the amount of time allowed each week, in the grades surveyed, for teaching music; (3) to discover the attitudes of teachers surveyed toward music and its relation to the over-all school program; (4) to discover their attitudes toward music teachers; (5) to receive suggestions from classroom teachers as to how the music program in grades four, five, and six could be improved to better benefit the children; and (6) to receive suggestions from classroom teachers as to improvements that could be made by the music teacher

Increasing Hospital Admissions for Pneumonia, England

This rise in recorded incidence from 2001 to 2005 was particularly marked among the elderly

VLBA Imaging of the OH Maser in IIIZw35

We present a parsec-scale image of the OH maser in the nucleus of the active galaxy IIIZw35, made using the Very Long Baseline Array at a wavelength of 18 cm. We detected two distinct components, with a projected separation of 50 pc (for D=110 Mpc) and a separation in Doppler velocity of 70 km/s, which contain 50% of the total maser flux. Velocity gradients within these components could indicate rotation of clouds with binding mass densities of ~7000 solar masses per cubic parsec, or total masses of more than 500,000 solar masses. Emission in the 1665-MHz OH line is roughly coincident in position with that in the 1667-MHz line, although the lines peak at different Doppler velocities. We detected no 18 cm continuum emission; our upper limit implies a peak apparent optical depth greater than 3.4, assuming the maser is an unsaturated amplifier of continuum radiation.Comment: 10 pages, 3 figure